The paper analyzes the dependence of LNG losses on the structural parameters of the tank. Methods of increasing the accuracy of calculations by considering the external operating conditions of the thermodynamic system are presented. The main parameters of loading operations are determined, such as the amount of gas needed to cool the tank, the amount of LNG losses during filling, and the dependence of pressure growth during drainage-free storage of cryofluid in the tank is also obtained. The paper presents a mathematical coefficient that determines the dependence of LNG losses depends on the ambient temperature. The verification of a mathematical model has been carried out, which makes it possible to estimate the loss of cryogenic fuel in a storage tank for various external conditions with sufficient accuracy for engineering calculations.