An experimental cryogenic evaporative cooling system for various objects such as IR signal receivers and biomaterials is considered in this paper. The parameters of the cooling system units, which include a cryostat vessel with a lid and a vacuum pipeline of the cryogenic evaporation unit, are the subject of study. The cryoproduct is liquid nitrogen. The paper presents thermal calculation of components most vulnerable to heat inflows of an experimental design of a cryogenic evaporation cooling system, as well as the design solution of the evaporator unit, cryostat, and module with temperature sensors. The results of experimental research are also given, which allow to make sure of the system efficiency.